Is Rage Against Red Meat a Red Herring? (Part IV-Conclusion)

Why you can have your steak, and eat it too!

If this is such a promising solution, why don’t we see an immediate, worldwide adoption of such agricultural practices? What roadblocks remain?

There is of course, the status quo. Current, conventional approaches have a track record of success both in the production of foodstuffs and in terms of economics for large-scale producers and industrial suppliers. For many, and understandably so, there is a mindset of, “if it ain’t broke, don’t fix it.” The problem with this perspective, is that from a sustainability point of view, the system is broke.

Another issue along those lines is the risk for the producer. As Kelly Lozensky confides,

“It doesn’t cost more to produce regenerative grains, but the RISK during transition is very high.  No Tillage, No synthetic fertilizer, no pesticide, no fungicide and no preharvest desiccant.”

The transition to regenerative farming involves a rehabilitation and reestablishment of a natural ecosystem. The length of time required as Kelly recounts, can be years. Starting in 2014;

Our soils tests  were calling for various degrees of fertility based on soil type.  We were also trying to manage input expenses by applying only what each soil was ‘needing.’… Some of our soil types called for no Nitrogen on ground.  This began a shift in our mindset where we began to consider a “more is less” approach when it came to synthetic fertilizer applications.  We observed that the soil types that didn’t receive fertilizers, actually had less disease and pest issues. We were very surprised by this and began to consider what was going on under our feet was way more complex than we had known.  We began to ask questions:  why are our plants more resistant on soils with no synthetic amendments?  Could our other soil types be capable of this same resilience?  The answer was yes, but it took us 5 years to wean off the “junk”.  Our soils were addicted, and we slowly took away the “drugs” until we were completely free of synthetic fertilizer in spring of 2019.

A final, but perhaps the most significant obstacle is the 300 pound soybean sitting in the room. Worldwide agribusiness is a huge and sprawling enterprise. As mentioned previously, many of these companies and concerns provide the raw materials, the technical expertise, assistance, and financial support for many of the world’s farmers and growers. This is particularly true, as was mentioned, in many Secondary and Third World countries and economies.

Many of those governments simply don’t have the resources to support their farmers and producers, and thus multinationals fill that void. However, these businesses have deep and strong roots even within First world economies. In India, for example, many poor farmers were forced as a result of economics to give up the farming of native heirloom species (which were purchased by agribusiness entities) and grow GMO crops with conventional methods and techniques. So disruptive were these interventions, that there was national concern due to the number of the small farmers who ended up committing suicide as a result of the distressing circumstances.

Such enterprises have zero use for solutions that don’t involve their products. Regenerative approaches, by any name, embrace the use of modern technologies to assist their efforts. Where they differ is in their independence from, their lack of dependence upon, artificial chemical additives in the form of fertilizers, herbicides, and pesticides. There is still a market for GMO plants.

However, the genetic modifications might be ones like those used in the creation of “golden rice.” Here the genetic modification was to add a beta-carotene producing gene to rice. This provides the large portion of the world that uses rice as a staple grain to add beta-carotene (the substrate for humans to produce vitamin A) to their diet. What there is not a need for, are the current proprietary GMO plants that are engineered to withstand a chemical maelstrom and make it to market.

Shifting our perspective to embrace and actualize positive solutions, to empower us as individuals in our relationship with the food we eat, is what Culinary Medicine is all about. So what are specific steps that we as individuals can take?

Give a damn about sustainability. That means eating foods that sustain you, and not in the “food as fuel,” or “food as medicine,” approach. That narrow, nutrition only perspective robs us of one of life’s great experiences: the fantastic flavors and textures found in eating real food. You’re not an automobile to be filled up and driven until your engine no longer works. You’re a human being, put here for a purpose and with an opportunity to enjoy the simple pleasures and genuine happiness that comes from enjoying authentic food with friends and family. That turns out to be a powerful antidote to the many challenges – and diseases – of our modern lives.

Sustainability also refers to the larger planetary collective that is been the focus of this series of articles. Here are three simple steps to help get you started. Ultimately, the path is yours, the choices are yours alone. Our relationship with food is exactly that, our relationship. It is an individual experience that only you will ever know. Make each one the most joyous it can be.

  1. Eat less meat. We are inundated with advertising and messaging designed to convince us that quantity is value. But if each chicken nugget is costing us $0.15 (as they are obviously making a profit), it is not difficult to extrapolate to the quality level of the product. Shift your perspective on the value of the food you eat from how much you get to the quality of the comestibles. You might eat less meat, less often. But by substituting quality over quantity, and creating an environment to truly enjoy your meal, you can have a far richer experience.
  2. Eat more plants. Most people in the United States and other industrialized nations subsist on a handful of plant varieties, most of them conventionally produced GMOs. Try experiencing or creating dishes that feature authentic ingredients or heirloom varietals. Local, responsibly grown fruits and vegetables might be ugly, but they have character. And in the kitchen, character means flavor.
  3. Know your food. Whatever you are sourcing, whether it is meat, poultry, fish, seafood, or fruits and vegetables; taking the time and effort to connect with your food is the fundamental first step in establishing a positive relationship with the food you eat. It’s a basic instinct of all great chefs. When you go to purchase your ingredients, just ask and answer these three questions:
    1. How was it bred? For example, is this an heirloom varietal or GMO crop?
    2. What was it fed? For example, i this grown without fertilizers and pesticides on a regenerative farm or was a grown using conventional, industrial agriculture?
    3. Where was it led? For example, was this simply packaged after harvesting or was it ultra-processed into the final product?


Red meat – essentially all or none – is where this discussion started. All too often, the answers are presented as an oversimplified “yes” or “no” choice. All too often, that is the result of ignorance born from limited viewpoint, or from purposeful misdirection as a consequence of undisclosed agendas, or some combination of both. Yet if we take the time, if we are willing to take a step back and shift our perspective, engage in dialogue, and entertain other possibilities; new opportunities can arise. I believe this is such a moment.

As an epicurean adventurer for all things edible, no doubt I have a very real ‘steak’ in the outcome. Feeding the world and feeding ourselves in concert with nature and the planet may seem an elusive holy grail. But the choices and the grail are very real. It is up to us. But as the ancient Guardian warned Indiana Jones, “You must choose. But choose wisely, as the true grail will bring you life, and the false grail will take it from you.”



EFSA . (2009). Modification of the residue definition of glyphosate in genetically modified maize grain and soybeans, and in products of animal origin. . EFSA Journal, 7: 1310 -1317.

A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Michigan State University, Oregon State University, and University of California at Davis. . (1993, September). Dicamba. Retrieved from Extoxnet:

A Pesticide Information Project of Cooperative Extension Offices of Cornell University, Michigan State University, Oregon State University, and University of California at Davis. (1994, May). Glyphosate. Retrieved from Extoxnet:

Abdel-Mallek, A., Abdel-Kader, M., & Shonkeir, A. (1994). Effect of glyphosate on fungal population, respiration and the decay of some organic matters in Egyptian soil. . Microbiol. Res., 149: 69-73.

Ackerman, Z. (2020, August 10). Regenerative Organic Can Feed the World. Retrieved from

Agapito-Tenfen, S., Vilperte, V., Benevenuto, R., Rover, C., Traavik, T., & Nodari, R. (2014). Effect of stacking insecticidal cry and herbicide tolerance epsps transgenes on transgenic maize proteome. . BMC Plant Biol , 14:346. doi:10.1186/s12870-014-0346-8 .

Albert, M., Mathan, V., & Baker, S. (1980 ). Vitamin B12 synthesis by human small intestinal bacteria. Nature. , 283(5749):781-2.

Anadón, A., del Pino, J., Martínez, M. A., Caballero, V., Ares, I., Nieto, I., & Larranaga-Martínez, M. R. (2008). Neurotoxicological effects of the herbicide glyphosate. Abstracts / Toxicology Letters , 180S: S32–S246.

Antoniou, M., Habib, M., Howard, C. V., Jennings, R., Leifert, C., & Nodari, R. (2012). Teratogenic effects of glyphosate-based herbicides: divergence of regulatory decisions from scientific evidence. doi:10.4172/2161-0525.S4-006.

Astiz, M., de Alaniz, M., & Marra, C. (2012). The oxidative damage and inflammation caused by pesticides are reverted by lipoic acid in rat brain. Neurochem Int. , 61(7):1231-41. doi: 10.1016/j.neuint.2012.09.003.

Battaglin, W., Meyer, M., Kuivila, K., & Dietze, J. (2014). Glyphosate and its degradation product AMPA occur frequently and widely in U.S. soils, surface water, groundwater, and precipitation. . J Am Water Resour Assoc, 50:275–290. doi:10.1111/jawr.12159 .

Bellaloui, N., Reddy, K., Zablotowicz, R., Abbas, H., & Abel, C. (2009). Effects of Glyphosate Application on Seed Iron and Root Ferric (Iii) Reductase in Soybean Cultivars. Journal of Agricultural and Food Chemistry , 57(20):9569-74.

Beltrao, D. S., De-Campos, A. B., Moura, D. B., & Sousa, R. F. (2012). Changes in Soluble Manganese and Iron Concentrations of Tropical Wetland Soils as Influenced by Glyphosate Dosage. Communications in Soil Science and Plant Analysis , 44(6): 1092-1096 .

Benbrook, C. M. (2016). Trends in glyphosate herbicide use in the United States and globally . Environ Sci Eur , 28:3 DOI 10.1186/s12302-016-0070-0.

Benbrook, C. M., Butler, G., Latif, M. A., Leifert, C., & Davis, D. R. (2013). Organic Production Enhances Milk Nutritional Quality by Shifting Fatty Acid Composition: A United States–Wide, 18-Month Study. PLOS One, •DOI: 10.1371/journal.pone.0082429 .

Benítez Leite, S., Acosta, M., & Macchi, M. L. (2008). Congenital malformations associated with pesticides in Encarnación, Paraguay. Pediatrics, 121 Supplement 2.

Beuret, C., Zirulnik, F., & Giménez, M. (2005). Effect of the herbicide glyphosate on liver lipoperoxidation in pregnant rats and their fetuses. Reproduc Toxicol, 19(4):501-4.

Bode, R., Melo, C., & Birnbaum, D. (1884). Mode of action of glyphosate in Candida maltosa. Arch Microbiol, 140(1):83-5.

Bohn, T., Cuhra, M., Traavik, T., Sanden, M., Fagan, J., & Primicerio, R. (2014). Compositional differences in soybeans on the market: Glyphosate accumulates in Roundup Ready GM soybeans. Food Chemistry, 153: 201-215

Boles, R. G., Ment, L. M., Meyn, M. S., Horwich, A. L., Kratz, L. E., & Rinaldo, P. (1993). Short-term response to dietary therapy in molybdenum cofactor deficiency. Annals of Neurology, 34(5):742-744.

Bone, E., Tamm, A., & Hill, M. (1976 ). The production of urinary phenols by gut bacteria and their possible role in the causation of large bowel cancer. Am J Clin Nutr. , 29(12):1448-54.

Borggaard, O., & Gimsing, A. (2008). Fate of glyphosate in soil and the possibility of leaching to ground and surface waters: a review. Pest Manag Sci , 64:441–456. doi:10.1002/ps.1512.

Brändli, D., & Reinacher, S. (2012). Herbicides found in human urine. Ithaka J, 1:270–272.

Bretveld, R., Brouwers, M., Ebisch, I., & Roeleveld, N. (2007). Influence of pesticides on male fertility. Scand. J. Work Environ. Health, , 33:13-28.

Brewster, D., Warren, J., & Hopkins, W. (1991). Metabolism of glyphosate in Sprague–Dawley rats: tissue distribution, identification, and quantitation of glyphosate-derived materials following a single oral dose. Fundam Appl Toxicol , 17: 43-51.

Brown, K., & Arthur, J. (2007). Selenium, selenoproteins and human health: a review. Public Health Nutrition, 4(2b): 593-599

Brown, K., DeCoffe, D., Molcan, E., & Gibson, D. L. ( 2012). Diet-Induced Dysbiosis of the Intestinal Microbiota and the Effects on Immunity and Disease. Nutrients, 4(8), 1095-1119 doi:10.3390/nu4081095.

Cakmak, I., Yazici, A., Tutus, Y., & Ozturk, L. (2009). Glyphosate reduced seed and leaf concentrations of calcium, manganese, magnesium, and iron in non-glyphosate resistant soybean. Eur. J. Agron, 31:114-119.

Cancer, I. A. (2015). Carcinogenicity of consumption of red and processed meat. The Lancet,

Carman, J., Vlieger, H., Robinson, G., Clinch-Jones, C., & Haynes, J. E. (2013). A long term toxicology study on pigs fed a combined genetically modified (GM) soy and GM maize diet. J Org Syst, 8:38-54.

Carrington, D. (2017, July 14). Over 60% of breads sold in the UK contain pesticide residues, tests show. Retrieved from

Cattani, D., de Liz Oliveira Cavalli, V., Heinz Rieg, C., Domingues, J., Dal-Cim, T., & Tasca, C. (2014). Mechanisms underlying the neurotoxicity induced by glyphosate-based herbicide in immature rat hippocampus: involvement of glutamate excitotoxicity. Toxicol, 320:34–45. doi:10.1016/j.tox.2014.03.001 .

Cerdas, M. (2005). Chronic kidney disease in Costa Rica. Kidney International, 68 (Supplement 97 ): S31–S33.

Chang, F., Simcik, M., & Capel, P. (2011). Occurrence and fate of the herbicide glyphosate and its degradate aminomethylphosphonic acid in the atmosphere. . Environ Toxicol Chem , 30(3):548–555.

Chatsko, M. (2016, May 16). How Much Money Does Monsanto Make From Roundup? Retrieved from The Motley Fool:

Clair, E., Linn, L., Travert, C., Amiel, C., Séralini, G., & Panoff, J. (2012). Effects of Roundup and glyphosate on three food microorganisms: Geotrichum candidum, Lactococcus lactis subsp.cremoris and Lactobacillus delbrueckii subsp. bulgaricus. . Curr. Microbiol. , 64: 486–491.

Connolly, S. J., Sheldon, R., Roberts, R. S., Gent, M., & Investigators, T. V. (1999). The North American vasovagal pacemaker study (VPS) §2: A randomized trial of permanent cardiac pacing for the prevention of vasovagal syncope. JACC , 33:(1) 16-20.

Cook, R. (2017, January 4). Ranking Of States That Produce The Most Corn . Retrieved from Beef 2 Live:

Coupe, R., Kalkhoff, S., Capel, P., & Gregoire, C. (2012). Fate and transport of glyphosate and aminomethylphosphonic acid in surface waters of agricultural basins. . Pest Manag Sci , 68:16–30.

Cuhra, M. (2015). Review of GMO safety assessment studies: glyphosate residues in Roundup Ready crops is an ignored issue. Environ Sci Eur , 27:20. doi:10.1186/s12302-015-0052-7 .

Dallegrave, E., Mantese, F., Coelho, R., Pereira, J., Dalsenter, P., & Langeloh, A. (2003). The teratogenic potential of the herbicide glyphosate-Roundup in Wistar rats. Toxicol Lett, 30;142(1-2):45-52.

Devlin, A. S., Marcobal, A., Dodd, D., Nayfach, S., Plummer, N., Meyer, T., . . . .Fischbach, M. A. (2016). Modulation of a Circulating Uremic Solute via Rational Genetic Manipulation of the Gut Microbiota. Cell Host & Microbe, 20(6):709-715

Dille, A. (2014, November 18). Kansas Wheat. Retrieved from The truth about Roundup in wheat :

Eker, S., Ozturk, L., Yazici, A., Erenoglu, B., Romheld, V., & Cakmak, I. ( 2006). Foliar-applied glyphosate substantially reduced uptake and transport of iron and manganese in sunflower plants. J. Agric. Food Chem. , 54: 10019-10025.

El-Shenawy, N. S. (2009). Oxidative stress responses of rats exposed to Roundup and its active ingredient glyphosate. Environmental Toxicology and Pharmacology, 28(3): 379-385.

EPA; Office of Prevention, Pesticides and TC. (1993). Registration eligibility document: glyphosate, EPA 738-R-93-014. Washington, DC: EPA.

Eur Comm; Germany and Slovakia: . (2013). Renewal assessment report: glyphosate residue data. Volume 3 Annex B.6.1. Eur Comm.

Fasano, A. (2011). Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer. Physiol rev, 91(1):151-75. doi: 10.1152/physrev.00003.2008.

Fasano, A. U. ( 2012). Zonulin, regulation of tight junctions, and autoimmune diseases. Ann N Y Acad Sci., 258(1): 25–33. doi: 10.1111/j.1749-6632.2012.06538.x.

Fenster, M. (2018 (in press)). Food Shaman: The Art of Quantum Food. New York: Post Hill Press.

Fenster, M. S. (2014). The Fallacy of The Calorie: Why the Modern Western Diet is Killing Us and How to Stop It. New York, NY: Koehler Books.

Ferdman, R. A. (2015 , July 14). How corn made its way into just about everything we eat. Retrieved from Washington Post:

Forouhi, N., Koulman, A., Sharp, S., Imamura, F., Kröger, J., Schulze, M., . . . Wareham, N. (2014). Differences in the prospective association between individual plasma phospholipid saturated fatty acids and incident type 2 diabetes: the EPIC-InterAct case-cohort study. Lancet Diabetes Endocrinol. , 2:810–818. doi: 10.1016/S2213-8587(14)70146-9.

Fukouka, M. (1985). The Natural Way of Farming:Tthe Theory and Practice of Green Philosophy. New York: Bookventure.

Fukuoka, M. (1978). The One Straw a Revolution. New York: New York Review Books.

Fukuoka, M. (2012). Sowing Seeds in the Desert: Natural Farming, Global Restoration, and Ultimate Food Security. White River Junction, Vermont: Chelsea Green Publishing.

Ganson, R. J., & Jensen, R. A. (1988). The essential role of cobalt in the inhibition of the cytosolic lsozyme of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Nicotiana silvestris by glyphosate. Archives of biochemistry and biophysics. , 260: 85-93. 10.1016/0003-9861(88)90427-4. .

Gasnier, C., Dumont, C., Benachour, N., Clair, E., Chagnon, M.-C., & Séralini, G.-E. (2009). Glyphosate-based herbicides are toxic and endocrine disruptors in human cell lines. Toxicology , 262:184–191.

Gibney, M. J., Forde, C. G., Mullally, D., & Gibney, E. R. (2017). Ultra-processed foods in human health: a critical appraisal. The American Journal of Clinical Nutrition, 106(3):717–724, (2013, October 31). Glyphosate Facts: Transparency on safety aspects and use oif glyphosate-containing herbicides in Europe. Retrieved from

Gov.Uk. (2016, February 3). (PRiF) UDECoPRiF: Monitoring program. Retrieved from

Gravois, K. (2017, August 14). Sugarcane Ripener Recommendations. Retrieved from LSU Ag Center:–glyphosate

Gupta, S. (2017, December 21). If we are what we eat, Americans are corn and soy. Retrieved from CNN>com:

Han, X. (2016). A Review of the Food and Feed Safety of the EPSPS Protein. Research Gate, DOI: 10.13140/RG.2.2.15073.10081 .

Henrique Saes Zobiole, L., de OliveiraJr, R. S., Morgan Huber, D., Constantin, J., de Castro, C., de Oliveira, F. A., & de OliveiraJr, A. (2010). Glyphosate reduces shoot concentrations of mineral nutrients in glyphosate-resistant soybeans. Plant and Soil, 328(1–2): pp 57–69 .

Herbert, L., Vázquez, D., Arenas, A., & Farina, W. ( 2014 ). Effects of field-realistic doses of glyphosate on honeybee appetitive behaviour. J Exp Biol., 217(Pt 19):3457-64. doi: 10.1242/jeb.109520.

Hietanen, E., Linnainmaa, K., & Vainio, H. (1983). Effects of Phenoxyherbicides and Glyphosate on the Hepatic and Intestinal Biotransformation Activities in the Rat. Basic & Clinical Pharmacology & Toxicology, 53 (2):103-112.

Hoagland, R., & Duke, S. (1982). Biochemical effects of glyphosate [N-(Phosphonomethyl)glycine]. In D. Moreland, J. St. John, F. Hess, & (Eds), Biochemical Responses Induced by Herbicides (pp. 175–205.). Washington, DC: American Chemical Society.

Hokanson, R., Fudge, R., Chowdhary, R., & Busbee, D. (2007). Alteration of estrogen-regulated gene expression in human cells induced by the agricultural and horticultural herbicide glyphosate. . Hum Exp Toxicol , 26:747–752.

Hsiao, T. (2015). In Defense of Eating Meat. . J Agric Environ Ethics, 28, 277–291

Huggins, D. R., & Reganold, J. P. (2017, November 14). No-Till; The Quiet Revolution. Retrieved from USDA:

Hughes, D., Duarte-Salles, T., Hybsier, S., Trichopoulou, A., Stepien, M., Aleksandrova, K., . . . Jeneb, M. (2016). Prediagnostic selenium status and hepatobiliary cancer risk in the European Prospective Investigation into Cancer and Nutrition cohort. . Am J Clin Nutr., 104(2): 406-414 DOI: 10.3945/ajcn.116.131672 .

Hurst, R., Armah, C. N., Dainty, J. R., Hart, D. J., Teucher, B., Goldson, A. J., . . . Fairweather-Tait, S. J. (2010). Establishing optimal selenium status: results of a randomized, double-blind, placebo-controlled trial. Am J of Clin Nutr, 91:923–31.

Iglesias, P., B. M., Selgas, R., & Díez, J. (2017 ). Thyroid dysfunction and kidney disease: An update. Rev Endocr Metab Disord. , 18(1):131-144. doi: 10.1007/s11154-016-9395-7.

Iglesias, P., Selgas, R., Romero, S., & Díez, J. ( 2013 ). Selenium and kidney disease. J Nephrol., 26(2):266-72. doi: 10.5301/jn.5000213. .

J., J. P., & Jacques, J. R. (2012). Monocropping Cultures into Ruin: The Loss of Food Varieties and Cultural Diversity. Sustainability, 4:2970-2997 doi:10.3390/su4112970.

Jasper, R., Olivo Locatelli, G., Pilati, C., & Locatelli, C. (2012 ). Evaluation of biochemical, hematological and oxidative parameters in mice exposed to the herbicide glyphosate-Roundup. Interdiscip Toxicol. , 5(3): 133–140 doi: 10.2478/v10102-012-0022-5.

Jayasumana, C., Gunatilake, S., & Senanayake, P. (2014). Glyphosate, hard water and nephrotoxic metals: are they the culprits behind the epidemic of chronic kidney disease of unknown etiology in Sri Lanka? . Int J Environ Res Public Health , 11:2125–2147. doi:10.3390/i.

Jayasumana, Paranagama, P., Agampodi, S., Wijewardane, C., Gunatilake, S., & Siribaddana, S. (2015). Drinking well water and occupational exposure to Herbicides is associated with chronic kidney disease, in Padavi-Sripura. . Sri Lanka Environ Health , 14:6. doi:10.1186/1476-069X-14-6 .

Kelly, J. L., Friedberg, J. W., Calvi, L. M., van Wijngaarden, E., & Fisher, S. G. (2009). Vitamin D and Non-Hodgkin Lymphoma Risk in Adults: A Review. Cancer Investigation, 27(9): 942-951 .

Ketteler, M. (2006). Kidney failure and the gut: p-cresol and the dangers from within. Kidney International, 69(6):952-953.

Khaw, K., Friesen, M., Riboli, E., Luben, R., & Wareham, N. ( 2012). Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study. . PLoS Med, 9:e1001255. doi: 10.1371/journal.pmed.1001255.

Kim, Y., Hong, J., Gil, H., Song, H., & Hong, S. ( 2013). Mixtures of glyphosate and surfactant TN20 accelerate cell death via mitochondrial damage-induced apoptosis and necrosis. . Toxicol. In Vitro, 27: 191–197.

Kruger, M., Schrodl, W., Pedersen, I., & Shehata, A. ( 2014). Detection of glyphosate in malformed piglets. J Environ Anal Toxicol., 4:5.

Krüger, M., Shehata, A., Schrödl, W., & Rodloff, A. ( 2013). Glyphosate suppresses the antagonistic effect of Enterococcus spp. on Clostridium botulinum. Anaerobe., 20:74-8. doi: 10.1016/j.anaerobe.2013.01.005. .

Kumar, S., Khodoun, M., Kettleson, E., McKnight, C., Reponen, T., Grinshpun, S., & Adhikari, A. (2014). Glyphosate-rich air samples induce IL-33, TSLP and generate IL-13 dependent airway inflammation. Toxicology., 5;325:42-51. doi: 10.1016/j.tox.2014.08.008. .

Kwiatkowska, M., Jarosiewicz, P., Michałowicz, J., Koter-Michalak, M., Huras, B., & Bukowska, B. (2016). The Impact of Glyphosate, Its Metabolites and Impurities on Viability, ATP Level and Morphological changes in Human Peripheral Blood Mononuclear Cells. . PLoS ONE, 11(6): e0156946.

Laaksonen, D., Lindström, J., Lakka, T., Eriksson, J., Niskanen, L., Wikström, K., . . . Härkönen, P. (2005). Finnish diabetes prevention study. Physical activity in the prevention of type 2 diabetes: the Finnish diabetes prevention study. . Diabetes. , 54(1):158-165. doi: 10.2337/diabetes.54.1.158.

Larsen, K., Najle, R., Lifschitz, A., Mate, M. L., Lanusse, C., & Virkel, G. L. (2014). Effects of Sublethal Exposure to a Glyphosate-Based Herbicide Formulation on Metabolic Activities of Different Xenobiotic-Metabolizing Enzymes in Rats . International Journal of Toxicology, 33(4): 307-318 .

Li, Q., Fang, Y., Li, X., Zhang, H., g Liu, M., Yang, H., . . . Wang, Y. (2013). Mechanism of the plant cytochrome P450 for herbicide resistance: a modelling study. Journal of Enzyme Inhibition and Medicinal Chemistry , 28 (6): .

Livingstone, E., & Barigazzi, J. (2017, August 29). Italian pasta labels test limits of EU law. Retrieved from

Lorbek, G., Lewinska, M., & Rozman, D. (2011). Cytochrome P450s in the synthesis of cholesterol and bile acids – from mouse models to human diseases. The FEBS Journal, DOI: 10.1111/j.1742-4658.2011.08432.x.

Lu, W., Li, L., Chen, M., Zhou, Z., Zhang, W., Ping, S., . . . Lin, M. (2013). Genome-wide transcriptional responses of Escherichia coli to glyphosate, a potent inhibitor of the shikimate pathway enzyme 5-enolpyruvylshikimate-3-phosphate synthase. Mol. Biosyst. , 9: 522–530.

Ma, J., Bu, Y., & Li, X. (2014). Immunological and histopathological responses of the kidney of common carp (Cyprinus carpio L.) sublethally exposed to glyphosate. . Environ Toxicol Pharmacol , 39:1–8.

Maduro, L. M., & Snyder, F. (1998). We the Court: The European Court of Justice and The European Economic Constitution. Portland, Oregon: Hart Publishing.

Main, D. (2017, June 26). Monsanto Weed-killer Roundup causes cancer, says California. Retrieved from

Mariager, T., Madsen, P., Ebbehøj, N., Schmidt, B., & Juhl, A. (2013). Severe adverse effects related to dermal exposure to a glyphosate-surfactant herbicide. . Clin. Toxicol., 51: 111-113.

Mathus, T. L., .Townsend, D. E., & Miller, K. W. (1995). Anaerobic biogenesis of phenol and p-cresol from l-tyrosine. Fuel, 74(10): 1505-1508.

Meijers, B., De Loor, H., & Bammens, B. (2009). p-Cresyl sulfate and indoxyl sulfate in hemodialysis patients, . Clin J Am Soc Nephrol , 4:1932-1938.

Mesnage, R., Defarge, N., Vendômois, J., & Séralini, G.-E. (2015). Potential toxic effects of glyphosate and its commercial formulations below regulatory limits. Food and Chemical Toxicology. , 84 DOI 10.1016/j.fct.2015.08.012. .

Meyer, H., & Hilbeck, A. (2013). Rat feeding studies with genetically modified maize—a comparative evaluation of applied methods and risk assessment standards. Environ Sci Eur , 25:33. doi:10.1186/2190-4715-25-33 .

Micha, R., Afshin, A., Khatibzadeh, S., & Mozaffarian, D. (2014). Consumption of nuts and legumes and risk of incident ischemic heart disease, stroke and diabetes: a systematic review and meta-analysis. Am J Clin Nutr., 100:278–288. doi: 10.3945/ajcn.113.076901.

Micha, R., Michas, G., Lajous, M., & Mozaffarian, D. (2013). Processing of meats and cardiovascular risk: time to focus on preservatives. . BMC Med , 11:136. doi: 10.1186/1741-7015-11-136.

Micha, R., Peñalvo, J. L., Cudhea, F., Imamura, F., Rehm, C. D., & Mozaffarian, D. (2017). Association Between Dietary Factors and Mortality From Heart Disease, Stroke, and Type 2 Diabetes in the United States. JAMA, 317 (9): 913-924.

Micha, R., Wallace, S. K., & Mozaffarian, D. (2010 ). Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes: A systematic review and meta-analysis. Circulation. , 121(21): 2271–2283. doi:10.1161/CIRCULATIONAHA.109.924977.

Mikkelson, D., & Kasprak, A. (2017, July 26). The Real Reason Wheat is Toxic: Are U.S. farmers saturating wheat crops with Monsanto’s Roundup herbicide as a desiccant to facilitate a quicker harvest? Retrieved from

Moechnig, M., & Deneke, D. (2016, February 3). Harvest aid weed control in small grain. Retrieved from https://www.sdstate. edu/sdces/resources/crops/weeds/upload/07-FS953-Harvest-Aid-WeedControl-in-Small-Grain-2009.pdf.

Monsanto. (2005, June). Backgrounder: The History of Monsanto’s Glyphosate Herbicides. Retrieved from Backgrounder: The History of Monsanto’s Glyphosate Herbicides:

Monsanto Company. (1981). MRID No. 0081674, 00105995. . Monsanto.

Monteiro, C. A., Cannon, G., Lawrence, M., de Costa Louzada, M. L., & Pereira Machado, P. (2019). Ultra-processed foods, diet quality, and health using the NOVA classification system. Rome, Italy: Food and Agriculture Organization of the United Nations.

Monteiro, C. A., Cannon, G., Moubarac, J.-C., Levy, R. B., Louzada, M. L., & Jaime, P. C. (2016). The UN decade of nutrition, the NOVA ood classification and the trouble with ultra-processing. Public Health Nutrition, 21 (1): 5-17.

Moorman, T., Becerril, J., Lydon, J., & Duke, S. (1992). Production of hydroxybenzoic acids by Bradyrhizobium japonicum strains after treatment with glyphosate. J. Agric. Food Chem. , 289–293.

Mortensen, D., Egan, J., Maxwell, B., & Ryan, M. (2012 ). Navigating a critical juncture for sustainable weed management. . Bioscience, 62:75–84.

Myers, J., Antoniou, M., Blumberg, B., Carroll, L., Colborn, T., Everett, L., . . . Benbrook, C. (2016). Concerns over use of glyphosate-based herbicides and risks associated with exposures: a consensus statement. . Environmental Health, 15:19 DOI 10.1186/s12940-016-0117-0.

Negri, E. (2010). Sun Exposure, Vitamin D, and Risk of Hodgkin and Non-Hodgkin Lymphoma. Nutrition and Cancer, 62(7):878-882.

NIH. (2017, November 27). Glyphosate potassium. Retrieved from Pub.Chem:

Nomura, N., & Hilton, H. (2006). . The adsorption and degradation of glyphosate in five Hawaii sugarcane soils. . Weed Research. , 17. 113 – 121. 10.1111/j.1365-3180.1977.tb00454.x. .

Nývltová, E., Šut’ák, R., Žárský, V., Harant, K., Hrdý, I., & Tachezy, J. (2017). Lateral gene transfer of p-cresol- and indole-producing enzymes from environmental bacteria to Mastigamoeba balamuthi. Environ Microbiol, 19: 1091–1102. doi:10.1111/1462-29.

Oller, J., Kennedy, D., Seneff, S., Davidson, R., Haley, B. E., & Masters, R. (2016). Environmental Toxicants and Infant Mortality in the USA. eertechz Journal of Biological Research and Development., 1: 036-061. .

Paetow, L., McLaughlin, J., Pauli, B., & Marcogliese, D. ( 2013). Mortality of American bullfrog tadpoles lithobates catesbeianus infected by Gyrodactylus jennyae and experimentally exposed to Batrachochytrium dendrobatidis. J. Aquat. Anim. Health, 25: 15–26.

Paganelli, A., Gnazzo, V., Acosta, H., López, S., & Carrasco, A. (2010). Glyphosate-based herbicides produce teratogenic effects on vertebrates by impairing retinoic acid signaling. . Chem Res Toxicol, 23:1586–1595.

Pastor Project. (2021). Grazing Benefits. Retrieved from Pastor Project:

Patringenaru, I. (2007, June 18). What is Ailing the American Diet? Retrieved from This Week at UCSD:

Peraza, S., Wesseling, C., Aragon, A., Leiva, R., García-Trabanino, R., Torres, C., . . . Hogstedt, C. (2012). Decreased kidney function among agricultural workers in El Salvador. Am J Kidney Dis. , 59(4):531-40. doi: 10.1053/j.ajkd.2011.11.039. .

Poesen, R., Viaene, L., Verbeke, K., Augustijns, P., Bammens, B., Claes, K., . . . Meijers, B. (2015). Cardiovascular disease relates to intestinal uptake of p-cresol in patients with chronic kidney disease. BMC Nephrology, 15:87

Prata, F., Camponez do Brasil Cardinali, V., Lavorenti, A., Tornisielo, V. L., & Regitano, J. B. (2003). Glyphosate sorption and desorption in soils with distinct phosphorus level. Scientia Agricola, 60(1):175-180.

Pressly , Linda . (2014, May 14). Are pesticides linked to health problems in Argentina? Retrieved from BBC News:

Raff, A., Meyer, T., & Hostetter, T. (2008). New insights into uremic toxicity. Curr Opin Nephrol Hypertens, 17: 560-565.

Relyea, R. ( 2005). The impact of insecticides and herbicides on the biodiversity and productivity of aquatic communities. . Ecol. Appl., 15: 618–627.

Richard, S., Moslemi, S., Sipahutar, H., Benachour, N., & Séralini, G. (2005). Differential effects of glyphosate and Roundup on human placental cells and aromatase. Environ. Health Perspect., 113:716-720.

Rodriguez-Iturbe, B., & Johnson, R. J. (2006). Role of inflammatory cells in the kidney in the induction and maintenance of hypertension. Nephrology Dialysis Transplantation, , 21(2): 260–263, .

Romano, M., Romano, R., Santos, L., Wisniewski, P., Campos, D., & de Souza, P. (2012). Glyphosate impairs male offspring reproductive development by disrupting gonadotropin expression. . Arch Toxicol , 86:663–673.

Romano, R., Romano, M., Bernardi, M., Oliveira, C., & Furtado, P. (2010). Prepubertal exposure to commercial formulation of the herbicide glyphosate alters testosterone levels and testicular morphology. Arch. Toxicol., 84 :309-317.

Samsel, A., & Seneff, S. (2013). Glyphosate’s Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases. Entropy, 15: 1416-1463 doi:10.3390/e15041416.

Samsel, A., & Sneff, S. (2013; ). Glyphosate, pathways to modern diseases II: Celiac sprue and gluten intolerance. Interdiscip Toxicol. , 6(4): 159–184. doi: 10.2478/intox-2013-0026 .

Schettler, T., Solomon, G., Kaplan, J., & Valent, M. (2003). Generations at risk: how environmental toxicants may affect reproductive health in California. Cambridge ,MA: MIT Press.

Schuette, J. (1998). ENVIRONMENTAL FATE OF GLYPHOSATE. Sacramento, California: Environmental Monitoring & Pest Management , Department of Pesticide Regulation.

Sebiomo, A., Ogundero, V., & Bankole, S. (2012). The Impact of Four Herbicides on Soil Minerals. Research Journal of Environmental and Earth Sciences. , 4: 617-624. .

Senapati, T., Mukerjee, A., & Ghosh, A. (2009). Observations on the effect of glyphosate based herbicide on ultra structure (SEM) and enzymatic activity in diff erent regions of alimentary canal and gill of Channa punctatus. Journal of Crop and Weed , 5(1): 236–245.

Seralini, G.-E., Clair, E. M., R., G., S., D., N., & Malatesta, M. (2014). Long Term Toxicity of a Roundup Herbicide and a Roundup-toerant Genetically Modified Maize. Environmental Sciences Europe, 26:14.

Shalapour, S., Lin, X.-J., Bastian, I. N., Brain, J., Burt, A. D., Aksenov, A. A., . . . Karin, M. (2017). Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity. Nature, 551: 340–345 doi:10.1038/nature24302.

Shehata, A., Schrödl, W., Aldin, A., Hafez, H., & Krüger, M. (2013). The effect of glyphosate on potential pathogens and beneficial members of poultry microbiota in vitro. . Curr. Microbiol. , 66: 350–358.

Silva, V., Montanarella, L., Jones, A., Fernández-Ugalde, O., Mol, H. G., Ritsema, C. J., & Geissena, V. (2017). Distribution of glyphosate and aminomethylphosphonic acid (AMPA) in agricultural topsoils of the European Union. Science of The Total Environment,

Spisák, S., Solymosi, N., Ittzés, P., Bodor, A., Kondor, D., & Vattay, G. (2013). Complete genes may pass from food to human blood. PLoS One, 8:e69805. doi:10.1371/journal.pone.0069805 .

Sun, C. Y., Hsu, H. H., & Wu, M.-S. (2013). P-Cresol sulfate and indoxyl sulfate induce similar cellular inflammatory gene expressions in cultured proximal renal tubular cells. Nephrology Dialysis Transplantation, , 28(1): 70–78, .

Syngenta Corporation. (2021). Weed Resistance: Not If, But When. Retrieved from,to%2083%20million%20soybean%20acres.

Texas Wheat Board. (2014, November 21). Glyphosate-treated Wheat: Claims vs. Facts. Retrieved from Texas Wheat Board:

The European Food Safety Authority. (2003). Opinion of the Scientific Panel on Genetically Modified Organisms on Request from the Commission Related to the Safety of Food and Food Ingredients Derived from Herbicide-Tolerant Genetically Modified Maize in NK 603 for Which a Request for Placing on the. EFSA J, , 9:1-14.

Then, C., & Bauer-Panskus, A. (2017). Possible health impacts of Bt toxins and residues from spraying with complementary herbicides in genetically engineered soybeans and risk assessment as performed by the European Food Safety Authority EFSA. Environmental Sciences Europe., 29 DOI 10.1186/s12302-016-0099-0. .

Thongprakaisang, S., Thiantanawat, A., Rangkadilok, N., Suriyo, T., & Satayavivad, J. (2013). Glyphosate induces human breast cancer cells growth via estrogen receptors. Food Chem Toxicol, 59:129–136.

Trichopoulou, A., Bamia, C., & Trichopoulos, D. (2009). Anatomy of health effects of Mediterranean diet: Greek EPIC prospective cohort study. BMJ, 338:b2337 doi:10.1136/bmj.b2337.

USDA. (2013). Agricultural Marketing Service. Pesticide data program annual summary, program year 2011. In: Appendix C Distribution of Residues in Soybean by Pesticide. Washington, D.C:: U.S. Department of Agriculture.

USDA. (2017, March 3). Animal Feeding Operations. Retrieved from Natural Resources Conservation Service:

USDA. (2020, December 16). ERS Charts of Note. Retrieved from,genetically%20engineered%20(GE)%20seeds.

What is (2017, December 5). Fundamentals. Retrieved from What is

Whorton, D., Krauss, R., Marshall, S., & Milby, T. (1977). Infertility in male pesticide workers. Lancet, 805:. 1259-1261.

Wikoffa, W. R., Anforab, A. T., Liub, J., Schultz, P. G., Lesley, S. A., Peters, E. C., & Siuzdak, G. (2009 ). Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. PNAS.

Wikvall, K. (2001 ). Cytochrome P450 enzymes in the bioactivation of vitamin D to its hormonal form (review). Int J Mol Med. , 7(2):201-9.

Williams, G., Kroes, R., & Munro, I. (2000). Safety Evaluation and Risk Assessment of the Herbicide Roundup in Its Active Ingredient, Glyphosate, for Humans. . Regul Toxicol Pharmacol, 31:117-165.

Winther, K. H., Bonnema, S. J., Cold, F., Debrabant, B., Nybo, M., Cold, S., & Hegedüs, L. (2015). Does selenium supplementation affect thyroid function? Results from a randomized, controlled, double-blinded trial in a Danish population . European Society of Endocrinology, 172: 657-667 doi: 10.1530/EJE-15-0069 .

Younossi, Z. M., Koenig, A. B., Abdelatif, D., & Fazel, Y. (2016). Global epidemiology of nonalcoholic fatty liver disease—Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology, 64(1): 73–84 DOI: 10.1002/hep.28431.

Yousef, M., Salem, M., Ibrahim, H., Helmi, S., Seehy, M., & Bertheussen, K. (1995). Toxic effects of carbofuran and glyphosate on semen characteristics in rabbits. J. Environ. Sci. Health B, 30 :513-534.

Zdziarski, I., Edwards, J., Carman, J., & Haynes, J. (2014). GM crops and the rat digestive tract: a critical review. . Environ Int, 73:423–433. doi:10.1016/j.envint.2014.08.018 .